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Blood samples (approximately 300 μl) were collected from the portal vein 10 or 30 min after the gastric administration because the time-course experiment estimated that active GLP-1 levels peaked at these time points
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BIBLIOGRAPHY 1 - Tirzepatide PI 2 - PMID 34170647 - Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes, NEJM (2021) 3 - PMID 35133415 - Effect of Subcutaneous Tirzepatide vs Placebo Added to Titrated Insulin Glargine on Glycemic Control in Patients With Type 2 Diabetes: The SURPASS-5 Randomized Clinical Trial, JAMA (2022) 4 - North Carolina Pharmacy Practice Act
