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Instead, they emphasize a physician-monitored protocol that uses GLP-1 peptides to help reset hunger cues, improve metabolic flexibility, and support behavioral changes that lead to real fat loss — not just water or muscle depletion

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A major challenge in MSTN inhibition is the potential for off-target effects, as other TGF-β family ligands, such as GDF11, activins, and BMPs, share the same receptor.[81] Thus, blocking MSTN may unintentionally disrupt other critical signaling pathways