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In vertebrates, the pre-proglucagon polypeptide is a product of the GCG gene, which encodes four peptide hormones: glucagon, glucagon-like peptide-1, glucagon-like peptide-2 and oxyntomodulin 50
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a The current device that delivers exenatide once weekly is the Bydureon BCise© pen (AstraZeneca plc, Cambridge, UK) that automatically administers the dose