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Moreover, the validity of the conducted research can be indirectly inferred by looking at analogous reviews made on a similar drug—metformin, where the relevance of conducting research on the effects of pharmacotherapy discernible in the disturbances of the qualitative and quantitative state of the intestinal microbiome was emphasized [11]
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N Engl J Med 2013;369:224-32.ArticlePubMed 452
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