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FDA Enforcement Actions and Safety Concerns In September 2025, the FDA issued over 50 warning letters to compounders marketing GLP-1 products as “generic” equivalents to FDA-approved drugs
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However, sensitivity analyses, which involved excluding individual studies, revealed that omitting one outlier study [22], characterized by substantial variability compared to the others, resulted in a significant increase in WL for the GLP-1RAs group (SMD = 0.82
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