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69 Increasing research has shown that in addition to the increased incidence of colorectal cancer, UC patients have an increased risk of extraintestinal cancers, 70 such as pancreatic cancer, 71 prostate cancer, 72 hepatocarcinoma, 73 and anal cancer
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There are six approved GLP-1 R peptide agonists (analogs of or modified derivatives of GLP-1), namely, exenatide (synthetic exendin-4), liraglutide, lixisenatide, dulaglutide, semaglutide and albiglutide, 12 all of which are formulated for subcutaneous injection and display a longer half-life than GLP-1, mostly due to their resistance to peptidases, such as DPP-IV
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