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Under the combined influence of stronger evidence, clearer safety boundaries, and patient values, GLP-1RAs may help shift PCOS management from isolated interventions toward a more integrated, life-course-oriented care framework
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Commonly reported adverse effects include: Injection site reactions (redness, pain, swelling) Fluid retention (peripheral oedema, joint pain, or carpal tunnel syndrome) — related to GH-mediated effects Glucose metabolism changes : tesamorelin can raise blood glucose levels and may worsen insulin resistance
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