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⚠️ Important Adverse Effects 🦴 Bone pain (most common) • Headache • Muscle aches • Leukocytosis • Injection-site reactions • Splenomegaly • Rarely, splenic rupture • Rarely, acute respiratory distress syndrome 🚨 Clinical Pearl A patient receiving Filgrastim who develops sudden left upper abdominal or left shoulder pain should be evaluated promptly because it may indicate splenic enlargement or, rarely, splenic rupture
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In the past, patients who regained weight after VSG were often unfairly blamed, with people assuming they had “stretched out their stomach” or “didn’t try hard enough.” However, modern medical understanding now recognizes that weight regain after VSG is largely driven by hormonal changes and metabolic adaptation
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