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Despite these differences, both drugs are semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist

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A meta-analysis of randomized controlled trials found that oral berberine reduced body weight by an average of 2.07 kg (about 4.5 pounds), BMI by 0.47 kg/m2, and waist circumference by 1.08 cm